Always note the scale on the drawing. Also, check that the printed physical scale of the drawing is correct.
Consider what would happen if you took a drawing that is the correct scale on a piece of U.S. Letter sized paper that is 8.5 inches x 11 inches (216 mm x 279 mm) and tried to print it on metric A4 paper that is 210 mm x 297 mm (8.27 inches x 11.7 inches). The printer may rescale the image to fit the different sized paper, which will result in an inaccurate print-out.
All of your measurements taken from these printed copies would be incorrect. So, not only should you verify the scale of the drawing, but you should verify its accuracy.
You should always check that the document was printed out accurately before making measurements and conversions. Make sure all construction drawings are printed out so that 1 unit of the printed document equals 1 unit of the original drawing. This can be done by checking the measurement of a dimensioned object or an object of known size.
Drawings can be inaccurate due to any form of copying or processing. While most original plots from a CAD file should be accurate (though human mistakes can and do happen), anything which has been plotted to "fit" the sheet of paper, rather than to a specific scale, is likely to be mis-scaled. All copies of drawings created or modified by printing (as distinct from plotting), photocopying, faxing, or turning into a PDF almost certainly are not accurate.